This seminar is open
for master and Phd students from the 2nd Master semester onwards. The seminar is an interdisciplinary seminar.
This seminar will be held online in the afternoons from 22.06. - 24.06. (with a preparation meeting on June 11).
Einschreibeschlüssel: Genomics
On each seminar day 2-5 students will present 15 minutes presentations followed by a common discussion. The publications are available online (here in moodle). The students will be assigned to their topics after the signing in period. If needed, each presentation and discussion will be followed by a short lecture (10 minutes given by the lecturer) summarizing again the most noteworthy points.
We have got used to the fact that we
can sequence (and meanwhile also manipulate) genomes. But how is a genome actually decoded - and how do you make sense of a "sequenced
genome"? This seminar discusses genomic methods
that explain how these technologies work and how they can be used to support
genetic studies.
Day 1: “What are genomic technologies?”. What are short reads and what are long reads? What can we do with them? How do we reconstruct genomes?
Day 2: "How can we use genomics to find causal mutations". We will look at genetic-mapping-by-sequencing.
Day 3: "The more surprising a result seems to be, the less likely it is to be true". We will be detectives and follow a genomic study that published wrong interpretations of their data and dig into scientific literature to see how this was corrected by the community.
Skills
At the end of the courses, students will be able to:
- Unterstand latest genomic technologies including the pros and cons
- Understand how genome sequencing can be used to find causal mutations
- Prepare and plan a genome sequencing experiment
- Know how to identify unreliably data in literature
Workload
Preparation for seminars: 4 h x 11 = 44 h
Seminar attendance: 6 h x 3 = 18 h
Preparation of presentation: 28 h
- Teacher: Finni Häußler
- Teacher: Korbinian Schneeberger
- Teacher: Sergio Tusso Gomez
- Teacher: Raúl Wijfjes